New Research Further Demonstrates Smoking Impact on Cutaneous Lupus

A newly published analysis of 838 patients with cutaneous lupus throughout Europe confirmed previous research results showing that smoking can worsen the severity of the disease and lessen the effectiveness of antimalarial treatment. Findings strongly suggest that people with cutaneous lupus should avoid smoking.

Key findings include:

  • More than half of patients with cutaneous lupus had ever smoked and 87.2% of this group had smoked before ever being diagnosed. Only 12.4% had never smoked before being diagnosed.
  • Disease was significantly more severe among patients who had ever smoked than in nonsmokers
  • Effectiveness of antimalarial treatment was significantly higher among nonsmokers than among patients who have ever smoked.

Study investigators concluded, “patients with cutaneous lupus erythematosus should be motivated to completely cease smoking; even a reduction in smoking can improve disease activity.”