Lupus Patients on Baseline Steroids Combined with Benlysta May Improve

Source: Lupus News Today

As reported by Lupus News Today: Results from two Phase 3 trials revealed that patients with systemic lupus erythematosus (SLE) can benefit from the recombinant human monoclonal antibody Benlysta (belimumab) when it is used with steroids.

The study, “Impact of concomitant medication use on belimumab efficacy and safety in patients with systemic lupus erythematosus,” published in Lupus, was developed by researchers at Germany’s University Hospital Mainz and colleagues.

Until recently, the standard of care for SLE patients included treatment with antimalarials, immunosuppressants, and steroids, either as single agents or in combination therapies. Benlysta was licenced for autoantibody-positive SLE patients in combination with those treatments in 2011.