At the Forum for Discovery, October 2004, more than 35 distinguished scientists in immunology and rheumatology gathered at the Yale Club in New York City.
Among the nationally renowned attendees was Kathryn Calame, PhD, professor of microbiology at Columbia University Medical Center, New York, who reviewed her ground-breaking research in gene regulation in the immune system. Her research group has identified a protein that regulates critical decision points determining the ability of B cells to make antibodies. This provides possibilities for modulating antibody production in autoimmune diseases.
James Allison, PhD, a leader in field of immunology and chairman of the immunology program at Memorial Sloan-Kettering Cancer Center, New York, shared his research which is focused on the mechanisms that regulate the immunological responses of T lymphocytes, particularly strategies to manipulate those responses in clinically relevant areas including autoimmunity, allergies, vaccinations, and tumor therapy.
Delivering the final scientific address was William Paul, MD, Chief, Laboratory of Immunology, NIAID-NIH, who serves as chairman of the LRI’s scientific advisory board.
Dr. Paul discussed the “homeostasis of T lymphocytes,” a presentation he had delivered last spring when he was honored to present the first Charles Janeway Memorial Lecture at Yale University School of Medicine. This honor commemorated Dr. Janeway, a leading immunologist who discovered many of the concepts that are the basis of immunology today.
A unique feature of the meeting was a reception and dinner offering patients and their families an opportunity to meet the scientists who are leading the effort to find a cure for lupus.
“This is exactly how science becomes productive,” commented Roberto Caricchio, MD, of the University of Pennsylvania.