Skin

Exposure to the rays of the sun clearly triggers lupus flares in some people, but not in others.

Keith Elkon, MD
University of Washington, Seattle, WA
Class of 2014

Theresa T. Lu, MD, PhD
Hospital for Special Surgery, New York, NY
Class of 2011

Could it be that ultraviolet light stimulates the skin to produce a “factor” that recruits white blood cells? One LRI researcher is looking into this novel hypothesis.

Vicki Kelley, PhD
Brigham and Women’s Hospital, Boston, MA
Class of 2007

Maybe the flares that certain people with lupus suffer from after sun exposure are due to a genetic irregularity in just a single base of DNA—one that activates a powerful immune system stimulant. An LRI researcher explored this bold hypothesis.

Victoria P. Werth, MD
University of Pennsylvania School of Medicine, Philadelphia, PA
Class of 2001

Sandra Wolin, MD, PhD
Yale University, New Haven, CT
Class of 2012