LRI Chicago

Midwest Determination, Hard Work, and Innovation Get the Job Done

Welcome to LRI Chicago, home of the new Midwest Division of the Lupus Research Institute.

LRI Chicago—dedicated to the LRI family throughout the Midwest. Visit us for

  • the latest on lupus research developments
  • ways to help
  • a place to connect with others and be inspired to hope for a better day for people with lupus

New 2009 LRI Novel Grant Recipient at University of Chicago

Timothy Niewold, MD, FACRTimothy Niewold, MD, FACR
University of Chicago

With his LRI grant, Dr. Niewold will pinpoint novel genes specifically associated with lupus in people of African-American ancestry-a population more commonly affected by lupus, and also far more likely to experience severe disease.

“The LRI was willing to fund this important work, which will improve our understanding of disease pathogenesis, and further our efforts to individualize therapy and make progress toward disease prevention.” – Dr. Niewold

Read more about Dr. Niewold’s work and the LRI’s 11 other grant recipients for 2009, a $3.6 million investment in lupus research work selected for its creativity, novelty, and the potential to drive scientific discovery to ultimately prevent, treat, and cure the complex disease of systemic lupus.

Midwest Researchers Deliver

It was just a few years ago that prominent members of the Chicago lupus community came together to form the national LRI Midwest base. See what's been accomplished by LRI-funded Midwest researchers in such a short time:

Marcus Clark, MDMarcus Clark, MD
University of Chicago

Dr. Clark has won a total of $5.9 million to further explore, explain, and expand on a major discovery initially funded by the LRI that no one else would take a chance on at the time.

Zhixin (Jason) Zhang, PhDZhixin (Jason) Zhang, PhD
University of Nebraska, Omaha, NE

As a result of his LRI-funded discoveries showing that lupus can result from B cells in overdrive, this Omaha investigator now has two NIH grants totaling $2.9 million. “Without the LRI we wouldn’t have been able to generate the preliminary data for the NIH grants. LRI support made this happen.” – Dr. Zhang

Mariana J. Kaplan, MDMariana J. Kaplan, MD
University of Michigan, Ann Arbor, MI

With LRI funding, Dr. Kaplan reports that her team “…found that the [female] lupus patients had abnormal vascular function that was impaired to the same extent seen in the heart disease patients — despite the fact that the lupus patients were approximately half the age.” In 2009 she was awarded a $1.5 million grant from the NIH's National Heart, Lung, and Blood Institute to continue the promising work on mechanisms of premature vascular disease in lupus.

Jochen Mattner, MDJochen Mattner, MD
Cincinnati Children’s Hospital Medical Center, OH

Thanks to LRI funding, Dr. Mattner has helped to confirm a long-held suspicion that certain bacterial or viral infections can elicit strong immune responses that prompt autoimmune illnesses such as lupus. He’s our most recent Midwest researcher to win NIH funding—$1.875 million.

There are so many ways that you can get involved and fight lupus! Join us today!