Marianthi Kiriakidou, MD
University of Pennsylvania, Philadelphia, PA
It’s now clear now that the genes a person inherits can make him or her more susceptible to lupus. Identifying these genes and figuring out how they cause disease is a major challenge in lupus research today.
Recently discovered MicroRNAs (miRNAs) are small RNA molecules that control the activity of one third of all our genes—and may well play a pivotal part in regulating the immune system. So far, their role in autoimmune diseases such as lupus has not been investigated.
By analyzing which miRNAs operate in lupus, Dr. Kiriakidou may well offer evidence for their use as new biomarkers or therapies.
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- B Cells
- Cardiovascular System
- Cell Signaling
- Central Nervous System
- Dendritic Cells
- Environmental Triggers
- Gender Matters
- General Immune System Function
- Human Lupus Biology
- Lupus Pregnancy
- New to Lupus
- New Treatments
- T Cells
- Target Identification
- Why the Lupus Immune System Reacts to Its Own DNA