- Connect with LRI:



- YouTube
- Change.org

Stephen C. Pelsue, PhD
University of Southern Maine, Portland, ME
2006 Genetics
The genes a person inherits may make him or her more susceptible to lupus.
Researchers have found that defective versions of the newly identified gene, Ttc7, results in a lupus-like autoimmune disease in mice.
With LRI funding, Dr. Pelsue is using sophisticated imaging and analytical tools to better understand this gene and its function in cells of the immune system.
He is using newly created mouse models to clarify how the gene contributes to the production of damaging autoantibodies—and thereby generate key insight into what causes such devastating autoimmune diseases as lupus.
On the go?
Text INFO to 50555 and opt-in to receive breaking news about lupus on your mobile phone.
Message and Data Rates May Apply. Text STOP to 50555 to STOP. Text HELP to 50555 for HELP. Full Terms
Topics
- B Cells
- Biomarkers
- Cardiovascular System
- Cell Signaling
- Central Nervous System
- Dendritic Cells
- Environmental Triggers
- Gender Matters
- General Immune System Function
- Genetics
- Human Lupus Biology
- Kidney
- Lupus Pregnancy
- New to Lupus
- New Treatments
- Skin
- T Cells
- Target Identification
- Why the Lupus Immune System Reacts to Its Own DNA














