- Connect with LRI:
- YouTube
- Change.org
Robert Winchester, MD
Columbia University College of Physicians and Surgeons, New York, NY
2004 Kidney
2004 Biomarkers
Dr. Winchester used his LRI grant to see if a particular pattern of gene activity in immune system cells he has identified as indicators of injury in kidney tissue, taken through biopsy, also appears in the blood.
Hopes are high that he is on track, so that a blood test for these biomarkers can be developed to watch for kidney problems, rather than subjecting people with lupus to repeated biopsies.
“If there are different predominant pathogenetic mechanisms of renal injury in lupus, then we can identify them molecularly and treat the patients differently and more appropriately.” – Dr. Winchester
Ongoing funding:
Based on his findings, Dr. Winchester was awarded a $40,000 New York Arthritis Foundation grant with Columbia University colleague Anne Davidson, MD, to look at TCR repertoires and kidney microarray data in the mouse.
